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The Air Force estimates that Wright-Patterson’s annual economic impact on the Dayton region is .1 billion.

Ohio had three city-regions in the top 30 biotech locations in the country, with Cleveland-Akron ranked #20, Columbus #22, and Cincinnati #28.

They include Cardinal Health at #17, Procter & Gamble at #22, Kroger at #23, Macy's at #103, Nationwide Insurance at #118, Goodyear Tire and Rubber at #141, Progressive Insurance at #161, American Electric Power at #172, Eaton Corporation at #194, and Owens Corning at #432.

Dayton is designated as the state's aerospace hub due to its high concentration of aerospace and aviation technology.

VRI, one of the nation's largest in-home medical health monitoring solutions companies, recently In 2011, Dayton was ranked the #3 city in the United States for excellence in health care.

The ranking is from Health Grade's list of America’s Top 50 Cities for Hospital Care.

In 2013, Ohio was ranked in the top ten states for best business climate by Site Selection magazine, based on a business-activity database. exports in 2009, with top destinations being Canada at .2 billion, followed by Mexico, China, United Kingdom, Greece, Brazil, Japan, Germany, France, and Australia.

The state was edged out only by Texas and Nebraska for the 2013 Governor's Cup award from the magazine, based on business growth and economic development.Makino's Global Titanium Research and Development Center is located in Mason.Nextant Aerospace has manufacturing facilities at the Cuyahoga County Airport.Medical device manufacturers employ 9,757 residents. Major hospital employers include the Cleveland Clinic Health System with 41,400 employees, Catholic Healthcare Partners in Cincinnati with 28,200, University Hospitals of Cleveland with 21,800, Ohio Health in Columbus with 15,300, Pro Medica in Toledo with 14,500, and Premier Health Partners in Dayton with 14,000.Welltower, an S&P 500 company headquartered in Toledo, is a major healthcare real estate firm.

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